Adverse effects of NASIDs
While NSAIDs are effective in relieving pain, fever and inflammation, they can cause unwanted side effects. Gastrointestinal side effects such as indigestion, stomach upset or stomach pain are commonly caused by NSAIDs. Use of NSAIDs can also cause ulcers and bleeding in the stomach and other parts of the gastrointestinal tract (gut). This is mainly because these medicines also attack the cyclooxygenase-1 enzyme that protects the stomach lining from normal stomach acid. common side effects of NSAIDs include Salt and fluid retention, Dizziness, Raised liver enzymes, High blood pressure, Less common side effects include: Ulcers of the oesophagus, Heart failure, Hyperkalaemia, Reduced kidney function, Bronchospasm, Skin infections.
- Raised liver enzyme
- Diarrhoea
- Dizziness
- Ulcers of oesophagus
- Salt and fluid retention
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- Toxicology - Pharmacology 2025 (France)
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