Pain Management 2023

Theme: Explore innovative approaches to pain relief and regain control of your life

Pain Management 2023

Renowned Speakers

Rob Russel
SCU Health System
USA

Adrian Shephard
Reckitt Benckiser
UK

Alex Maughan
Foundation Doctor at Papworth Hospital
UK

G Robert Jones
Cancer Research Unit
UK

Harish C Pant
National Institutes of Health
USA

Jean-Marc Lemaitre
Institute of Regenerative Medicine and Biotherapy
France

Mohammad Ali Rajput
Multan Medical and Dental College Pakistan
Pakistan

Pietro Mastroeni
University of Cambridge
UK

Raymond R Mattingly
Wayne State University School of Medicine
USA

Roger M. Leblanc
University of Miami
USA

Silke Salavati
The Roslin Institute University of Edinburgh
UK

Susan Welsh
Chief Safety Officer Sanofi
USA

Thomas Rich
University of South Alabama
USA

Varghese John
University of California
USA

Vivian SW Chan Fung
SafeWork NSW
Australia

Dear esteemed participants,

On behalf of the organizing committee, it is our utmost pleasure to welcome you to the 6^th International Conference and Exhibition on Pain Management. We are thrilled to have you join us for this highly anticipated event dedicated to the latest advancements and best practices in pain management.

This conference is designed to bring together leading experts, researchers, clinicians, and industry professionals from around the world to share their knowledge and experiences in the field of pain management. With a diverse range of topics and sessions, we aim to foster collaboration, innovation, and excellence in pain management.

Over the course of the conference, you can expect to engage in stimulating discussions, attend informative workshops, and hear from renowned speakers who are at the forefront of pain management research and practice. Our program covers a wide array of subjects, including pharmacological interventions, non-pharmacological approaches, interventional pain management techniques, and emerging therapies.

We would like to express our gratitude to all the participants, sponsors, and supporters who have contributed to making this conference possible. Your presence and active participation are essential in making this event a resounding success.

Once again, we extend our warmest welcome to all attendees of the Pain Management 2023 Conference. We hope that your time with us will be enriching, inspiring, and rewarding. We look forward to meeting you and sharing this incredible experience together.

Best regards,
[Organizing Committee]

Join us at the "6^th International Conference and Exhibition on Pain Management" hosted by Conference Series, where researchers, professors, scientific communities, delegates, students, business professionals, and executives are cordially invited. The event will take place in Rome, Italy, from December 04-05, 2023. This conference will provide a platform for engagement, empowerment, evolution, and exploration of knowledge for anesthesia, intensive care, pain medicine, palliative care, and related professionals. With a thematic focus on "Explore innovative approaches to pain relief and regain control of your life," our goal is to bring together esteemed experts and scholars in anesthesia, pain medicine, and palliative care to foster the advancement of core knowledge and major breakthroughs in these rapidly emerging fields.

The Pain Management Conference goes beyond serving as a platform for anesthesia specialists to enhance their knowledge of cutting-edge techniques in the field. It presents a comprehensive program that includes a symposium centered on pain management. This symposium equips delegates with valuable insights into the real-world challenges of enhancing healthcare and delivering effective pain management to patients.

Target Audience:

Chief/Head/Consultant Anaesthesiologists/ Anaesthetists
Anaesthesia Technicians/ Nurses (Anaesthetists)
Critical Care/ICU Nurses
Pain medicine consultants/ specialists and intensivists
Pharmacists Intensive care physicians
Institutes-Medical Schools Students
Manufacturing Medical Devices Companies
Business Entrepreneurs

Reasons to Attend:

Pain Management 2023 offers a global platform to showcase research findings, discuss diagnosis, prevention, and management strategies, and facilitate the exchange of ideas. By participating, you will contribute to the dissemination of knowledge in Anesthesia and Pain Medicine, benefiting both the academic community and the business sector.

The conference promises an engaging and informative program, featuring plenary lectures, symposia, workshops, poster presentations, and a variety of programs designed to cater to participants from across the globe. Join us for an exciting opportunity to enhance your understanding of pain management and stay abreast of the latest developments in the field

Track 1: Interventional Pain Management

Interventional pain treatment includes specialist procedures carried out in pain management clinics or centers, such as spinal cord stimulation and injections, to successfully treat and manage pain. The Pain treatment Centers provide advanced interventional pain treatment therapies given by a team of professional anaesthesiologists with specialized training in these techniques. Interventional pain treatment employs a multidisciplinary approach to provide comfort to patients suffering from a variety of illnesses such as persistent headaches, mouth or face pain, low back pain, muscular and/or bone pain, and neck pain.

Track 2: Anesthesia and Critical Care

Anesthesia and Critical Care are crucial medical disciplines that play a vital role in ensuring the safety and comfort of patients during surgical procedures and in critical care environments. Anesthesia encompasses the administration of medications to induce a controlled state of unconsciousness, alleviate back pain, and maintain physiological stability throughout surgery. Anesthesiologists are highly skilled professionals who diligently monitor patients' vital signs, administer appropriate anesthesia, and effectively address any potential complications that may arise. Critical care primarily focuses on providing specialized medical care to individuals who are critically ill, often in intensive care units (ICUs). Critical care specialists oversee the monitoring and treatment of patients with life-threatening conditions, ensuring their stability and managing intricate medical interventions.

Track 3: Pain Medicine

Pain medicine is a specialized field of medicine that focuses on the diagnosis, management, and treatment of pain. Pain, whether it is acute or chronic, can have a significant impact on a person's quality of life, and the goal of pain medicine is to alleviate suffering and enhance overall well-being. Pain medicine physicians adopt a comprehensive approach, combining a range of techniques and modalities to effectively address pain. These may include the use of medications, interventional procedures, physical therapy, rehabilitation, psychological therapies, and complementary or alternative therapies. Pain medicine physicians work closely with patients to understand the underlying causes of their pain, develop personalized treatment plans, and closely monitor progress. Through compassionate care and evidence-based practices, pain medicine specialists strive to reduce pain, improve functionality, and enhance the overall quality of life for individuals dealing with pain.

Track 4: Pain Management and Rehabilitation

Acute pain, which lasts for a short period, often indicates injury or disease, while chronic pain is typically associated with conditions such as headaches, lower back pain, or fibromyalgia. Fibromyalgia is characterized by pain in the back, hands, neck, shoulders, or pelvis, accompanied by fatigue or sleep disturbances. Rehabilitation programs are designed to provide individualized assessments, treatments, and follow-up plans for patients. These programs emphasize reducing medication dependency, implementing psychological treatments for conditions like depression and anxiety, offering family counseling, enhancing socialization skills, and providing educational or vocational counseling. Painful conditions such as migraines, tension headaches, and sinus headaches are also addressed. Migraine symptoms include a pounding headache, nausea, vomiting, and sensitivity to light. Treatment options include anti-nausea drugs, abortive medications, and preventive measures. Headache remedies often involve the use of pain relievers.

Track 5: Advances in Internal Medicine

The field of pain management has undergone a remarkable transformation with significant contributions from advances in Internal Medicine. These advancements have revolutionized the approach to diagnosing, understanding, and treating a wide range of pain conditions. One notable breakthrough is the development of advanced imaging techniques like magnetic resonance imaging (MRI) and functional MRI (fMRI), which enable enhanced visualization and evaluation of pain-related abnormalities within the central nervous system. Internal medicine specialists, collaborating with multidisciplinary teams, play a pivotal role in implementing these innovations, providing patients with personalized and comprehensive care tailored to their specific pain conditions. The integration of these advances in internal medicine has significantly advanced our understanding, diagnosis, and treatment of pain, instilling fresh hope and relief for individuals grappling with both chronic and acute pain

Track 6: NSAIDs and Analgesics

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely recognized as one of the most prevalent forms of pain relief medication worldwide. According to the American Gastroenterological Association, over 30 million Americans rely on NSAIDs daily to alleviate headaches, sprains, arthritis symptoms, and everyday discomforts. These medications not only provide pain relief but also possess fever-reducing and anti-inflammatory properties. NSAIDs function at a chemical level by inhibiting specific enzymes known as Cox-1 and Cox-2 enzymes, which are responsible for producing prostaglandins. By impeding these enzymes, NSAIDs effectively reduce the production of prostaglandins, leading to diminished swelling and decreased pain. Various types of NSAIDs are available over the counter, including aspirin (Bayer, Bufferin, Excedrin), ibuprofen (Advil, Motrin IB), and naproxen (Aleve). Opioid analgesics have been commonly used for the treatment of acute and chronic pain. Morphine is the most frequently employed opioid analgesic in postoperative situations, although some practitioners may prefer alternative agents such as hydromorphone. Opiate pain relievers are potent medications that can be highly effective in managing pain, particularly following injuries or surgical procedures. It is crucial to use these medications precisely as prescribed by a doctor to ensure their safe and proper usage. However, extended use of opioids carries a risk of addiction. Commonly utilized opioid analgesics for pain relief include codeine, fentanyl, hydrocodone, hydrocodone/acetaminophen, and meperidine. It is important to note that there are potential side effects associated with these medications, although they are less common. These may include ulcers of the esophagus, heart failure, hyperkalemia, reduced kidney function, bronchospasm, and skin infections.

Track 7: Classification of pain relief analgesics

Pain relief analgesics can be categorized based on their mechanism of action and potency, allowing for a comprehensive understanding of their diverse applications. Non-opioid analgesics, which include nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen, are frequently utilized for managing mild to moderate pain. By inhibiting the production of prostaglandins, which contribute to inflammation and pain, these medications effectively alleviate discomfort. On the other hand, opioid analgesics such as morphine, oxycodone, and codeine are potent pain relievers that bind to opioid receptors in the central nervous system, delivering robust pain relief. Generally reserved for moderate to severe pain, opioid analgesics come with potential side effects and the risk of dependence.

Track 8: Pharmacological Approaches for Pain

Analgesic drugs, commonly known as pain relievers, encompass a range of medications including nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, narcotics, antidepressants, anticonvulsants, and others. NSAIDs and acetaminophen are available both over-the-counter and by prescription, often serving as the initial pharmacological treatment for pain. These drugs can also be used as adjuncts to other prescribed therapies. NSAIDs, such as aspirin, ibuprofen (Motrin, Advil, Nuprin), naproxen sodium, and ketoprofen (Orudis KT), are primarily used to alleviate pain caused by inflammation. They achieve this by blocking the production of pain-enhancing neurotransmitters, like prostaglandins. Acetaminophen, while effective in pain relief, has limited anti-inflammatory properties. Narcotics, on the other hand, are potent pain relievers used for severe or intense pain, often employed in cancer pain management or acute cases unresponsive to NSAIDs and acetaminophen. Narcotics fall into two categories: opiates, derived from opium found naturally in certain poppy species, and opioids, synthetic drugs based on opium's structure. Opiates include morphine and codeine, while opioids encompass substances like oxycodone, methadone, and meperidine. These medications are available only with a doctor's prescription.

Track 9: Non-Pharmacological Approaches for Pain

Non-pharmacological approaches play a significant role in achieving effective pain relief and are often well-received by patients. While certain measures, such as the use of hot or cold packs, are occasionally recommended, their efficacy remains insufficiently researched. Complementary therapies for pain management are frequently sought out by patients and necessitate evaluation to determine their potential role in palliative care settings. Studies have been conducted on patient education regarding cancer pain management, revealing that educational interventions can have a modest yet clinically significant impact on pain, highlighting the underutilization of this strategy. Non-pharmacological methods used in pain management can be categorized in various ways. Generally, they are classified as physical, cognitive, behavioral, and other complementary methods, or as invasive or non-invasive methods. Non-invasive techniques include meditation, progressive relaxation, guided imagery, rhythmic breathing, biofeedback, therapeutic touch, transcutaneous electrical nerve stimulation (TENS), hypnosis, music therapy, acupressure, and hot and cold treatments. Among the invasive methods, acupuncture is the most well-known and commonly used. It is believed that these methods modulate pain transmission by influencing the gates through which pain signals travel to the brain or by promoting the release of natural pain-relieving substances, such as endorphins

Track 10: Regenerative Medicine

Regenerative medicine is an ever-evolving field dedicated to leveraging the innate healing mechanisms of the body to repair and rejuvenate damaged tissues and organs. This interdisciplinary approach encompasses a range of strategies, including stem cell therapy, tissue engineering, gene therapy, and biomaterial utilization, all aimed at fostering tissue regeneration and functional recovery. Stem cells, renowned for their remarkable ability to differentiate into diverse cell types, play a pivotal role in regenerative medicine. They can be sourced from various origins such as bone marrow, adipose tissue, or embryonic sources and are employed to replenish or restore impaired cells and tissues. Tissue engineering merges cells, scaffolds, and growth factors to fabricate synthetic organs or tissues that can be transplanted into the body, facilitating the restoration of function. Gene therapy entails delivering therapeutic genes to target cells, with the objective of rectifying genetic abnormalities or stimulating tissue mending processes.

Track 11: Arthritis & Inflammation

Inflammation is a process by which the body's white blood cells and substances they produce protect us from infection with foreign organisms, such as bacteria and viruses. However, in some diseases, like arthritis the body's defence system the immune system triggers an inflammatory response when there are no foreign invaders to fight off. In these diseases, called autoimmune diseases, the body's normally protective immune system causes damage to its own tissues. The body responds as if normal tissues are infected or somehow abnormal.

Track 12: Pain Assessment Tools

These practice tools are available to help healthcare professionals diagnose and treat pain more appropriately in their patients. Pain is often regarded as the fifth vital sign in regard to healthcare because it is accepted now in healthcare that pain, like other vital signs, is an objective sensation rather than subjective. Most pain assessments are done in the form of a scale. The scale is explained to the patient, who then chooses a score. A rating is taken before administering any medication and after the specified time frame to rate the efficacy of treatment. Pain assessment tools mainly includes pain history or clinical history it includes general medical history and specific pain history intensity, location, pathophysiology etc. Uni-dimensional tool is simple easy and very useful mainly includes verbal descriptor scale, verbal numeric rating scale, visual analogue scale, wong-baker facial pain rating scale. Multidimensional instruments provides more complex information about pain, for assessing chronic pain and those are time consuming.

Track 13: Cancer Pain Management

There are several causes of cancer pain, however usually cancer pain happens once a tumour presses on nerves or body organs or once cancer cells invade bones or body organs. Cancer treatments like therapy radiation, or surgery conjointly might cause pain. Cancer pain is acute or chronic. Acute pain is owing to injury caused by AN injury and tends to solely last a brief time. For instance, having an operation will cause acute pain. The pain goes once the wound heals. Within the in the meantime, painkillers can typically keep it in check. Chronic pain is pain caused by changes to nerves. Nerve changes might occur owing to cancer pressing on nerves or owing to chemical produced by a tumour. It may also be caused by nerve changes owing to cancer treatment. The pain continues long once the injury or treatment is over and may vary from delicate to severe. It is there all the time and is additionally referred to as persistent pain. Chronic pain is tough to treat, however painkillers or alternative pain management strategies will usually with success management it.

Track 14: Paediatric Pain Management

Chronic pain may be a growing downside among paediatric and adolescents, with some epidemiologic studies indicating that roughly half-hour of youngsters and adolescent’s expertise pain that lasts for three months or longer. The foremost common paediatric chronic pain complaints mainly migraine repeated abdominal pain, and general contractile organ pain, together with limb pain and back pain. Chronic pain is usually related to practical incapacity. Within the paediatric population this incapacity most often manifests as college impairment, problem maintaining social contacts, slashed participation in recreational activities, impairments in health connected quality of life, and a rise in health care utilization. As a result, these patient’s actual high prices on the health care system.

Track 15: Orofacial Pain

Orofacial pain is a general term covering any pain perceived in the head which is felt in the mouth, jaws and the face. Orofacial pain is a common symptom, and there are many causes. Orofacial pain has been defined as "pain localized to the region above the neck, in front of the ears and below the orbitomeatal line, as well as pain within the oral cavity, pain of dental origin and temporomandibular disorders". It is estimated that over 95% of cases of orofacial pain result from dental causes (i.e. Toothache caused by pulpitis or a dental abscess). However, some orofacial pain conditions may involve areas outside this region, e.g. temporal pain in TMD.Toothache, or odontalgia, is any pain perceived in the teeth or their supporting structures (i.e. the periodontium). Toothache is therefore a type of orofacial pain. Craniofacial pain is an overlapping topic which includes pain, face, and related structures, sometimes including neck pain. All other causes of orofacial pain are rare in comparison, although the full differential diagnosis is extensive.

Track 16: Pain Management Nursing

The nurse’s primary commitment is to the health, welfare, comfort and safety of the patient. Self-awareness, knowledge of pain and pain assessment, and knowledge of the standard of care for pain management enhances the nurse’s ability to advocate for and assure effectivepain management for each patient. When advocating for the patient, it is crucial that the nurse utilize and reference current evidence-based pain management standards and guidelines. The role of nurse is responsible and accountable to ensure that a patient receives appropriate evidence-based nursing assessment and intervention which effectively treats the patient’s pain and meets the recognized standard of care.

Track 17: Clinical Manifestations & Epidemiology of Pain

Pain is described by the patient mostly in terms such as stabbing, burning, tearing, squeezing, etc. Acute pain is accompanied by a stress response consisting of increase in blood pressure, tachycardia, pupillary dilatation, and high plasma cortisol levels. This may be accompanied bylocal muscle contraction. Four broad categories of pain are generally nociception, pain perception, pain behaviours. Chronic pain affects 20% of the European population and is commoner in women, older people, and with relative deprivation. Its management in the community remains generally unsatisfactory, partly because of lack of evidence for effective interventions. Good epidemiological research on chronic pain provides important information on prevalence and factors associated with its onset and persistence. Improving our understanding of associated factors will inform our clinical management, limiting severity, and minimizing disability.

Track 18: Neuropathic Pain and Neuro Orthopaedics

Neuropathic pain caused by impairment or disease affecting the somatosensory nervous system. Neuropathic pain can be contrasted to nociceptive pain that occurs when someone experiences an acute injury. This type of pain is typically short-lived and generally quite responsive to common pain medications in contrast to neuropathic pain. Neuro-orthopaedic service offers the latest advances in diagnosis and treatment to patients whose arms or legs are impaired by brain injury, stroke, anoxia, central nervous disorders, or orthopaedicconditions.

Track 19: Acute Pancreatitis

Acute pancreatitis is an inflammatory condition of the pancreas that is painful and at times deadly. Despite the great advances in critical care medicine over the past 20 years, the mortality rate of acute pancreatitis has remained at about 10%. Inflammation of the pancreatic tissue can be divided into chronic and acute inflammation depending on the degree of resolution of the tissue inflammation. Over 80% of all cases of acute pancreatitis are due to gallstones or the alcohol abuse. Severe abdominal pain is the hallmark symptom of patients suffering from acute pancreatitis as well as of chronic pancreatitis. The successful treatment of patients with acute pancreatitis has three prerequisites:

1) An adequate and early fluid resuscitation

2) Proper nutritional support and

3) An adequate pain management.

Track 20: Pain Management Market

Globally pain management devices market is valued at an estimated USD 3.08 Billion in 2016 and is projected to grow at a CAGR of 8.5% during the forecast period of 2016 to 2021. Several factors, such as the mounting demand for long-term pain management among the geriatric population, large patient population base, adverse effects of pain medications, progress ofnovel pain management device, conventional compensation scenario for spinal cord stimulation (SCS) devices in established countries, and high proven efficiency of pain management device for the treatment of chronic pain are driving the growth of the global market.

This report covers three major pain management device types, namely, neurostimulator devices, ablation devices, and analgesic infusion pumps. The neurostimulator devicessegment is expected to witness the highest growth and account for the largest share of thepain management devices market in 2016. This can be attributed to the advantages of neurostimulator over alternative therapies for managing chronic pain. Also, the long-term cost efficiency and technological developments in neurostimulator devices are contributing to the growth of this market segment.

Based on application, the global pain management device market is segmented into neuropathic pain, cancer pain, facial pain & migraine, musculoskeletal pain, and others. Theneuropathic pain application segment is estimated to witness the maximum growth during the forecast period, principally due to the presence of substantial clinical evidence in the favour of high efficacy of pain management device in neuropathic pain treatment, favourable reimbursement scenario, development of novel neuropathic pain management device, large patient population base, rising geriatric population across the globe, and side effects of drugs used to treat neuropathic pain.

Track 21: Pain Control Techniques

To prepare for any chronic pain coping technique, it is important to learn how to use focus and deep breathing to relax the body. Pain control techniques mainly involves altered focus. This is a favourite technique for demonstrating how powerfully the mind can alter sensations in the body. Focus your attention on any specific non-painful part of the body and alter pain sensation in that part of the body. Dissociation as the name implies, this chronic pain technique involves mentally separating the painful body part from the rest of the body, or imagining the body and mind as separate, with the chronic pain distant from one’s mind. Sensory splitting: this technique involves dividing the sensation into separate parts.

Mental anaesthesia: this involves imagining an injection of numbing anaesthetic (like Novocain) into the painful area, such as imagining a numbing solution being injected into your low back. Mental analgesia building on the mental anaesthesia concept, this technique involves imagining an injection of a strong pain killer, such as morphine, into the painful area. Alternatively, you can imagine your brain producing massive amount of endorphins, the natural pain relieving substance of the body, and having them flow to the painful parts of your body.

Pain Management 2023 Market Analysis

The growth of the global pain management drugs and devices market is majorly due to the well-established business of painkiller medications as the first line of treatment. In recent years, the increasing reliance on their prolonged use and a greater understanding of their side-effects have led to the growing use of device-based pain management therapies. Presently, at the country level, economic factors play a significant role in the management of financial implications for hospitals. Postsurgical pain is one of the primary focuses of hospitals, where the cost of monitoring and the treatment of adverse effects creates the major demand for pain management drugs and devices.

The current market is gradually adopting more non-opioid medications to suppress the addiction toward opioids and certain well-established painkillers in the market. There are several non-opioid drugs with mechanisms of action that are currently in early and late-stage development. The federal authorities in multiple countries are shifting to alternative approaches, and thus, fast-tracking those drugs to market approval. The shift is expected to be gradual, and thus pain management has very attractive growth prospects between 2019 and 2024.

Scope of the Report

This report includes an in-depth study of the global pain management market (henceforth, referred to as the ‘market studied’). Pain is defined as an unpleasant sensation in the body, owing to ongoing or impending tissue damage. Pain management is one of the most frequently dealt-with issues by clinicians for any disease. Pharmacological therapy is the first line of therapy, followed by treatment via devices in severe pain management cases.

Key Market Trends

Cancer Pain Segment is expected to Exhibit the Fastest Growth Rate over the Forecast Period

Pain during cancer occurs the most when a tumor presses on to the bones, nerves, or organs. The pain may vary according to the affected location. Chemotherapy, Radiotherapy, and Surgery can also cause pain. Certain painful conditions are likely to occur more in patients with a suppressed immune system, which is often a result of these therapies.

Pain caused by cancer can be treated. About nine out of ten cancer patients suffering from pain find relief by using a combination of medications. Many medicines are used for pain management in cancer patients. Some drugs are general pain relievers, while other target specific types of pain may require a prescription. The increasing incidences of various forms of cancer are likely to directly lead to an increase in cancer pain cases, the treatment of which, both through drugs and devices, is expected to contribute to the market growth.

North America Captured the Largest Market Share and is Expected to Retain its Dominance

North America holds the largest share in the global pain management market, with the United States being the largest contributor to its revenue. According to the data published by the Centers for Disease Control and Prevention (CDC), in 2016, approximately 20.4% of adults in the United States (which is about 50.0 million) were suffering from chronic pain and 8.0% of adults in the country (which is about 19.6 million) were suffering from high-impact chronic pain, with higher prevalence associated with advancing age.

Conference Highlights

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Conference Date	December 04-05, 2023
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